01/13/2015

| Publication | A new antibiotic kills pathogens without detectable resistance

Uncultured bacteria make up approximately 99% of all species in external environments, and their study could lead to the discovery of new antibiotics. Lately antibiotic resistance has been spreading much faster than the introduction of antibiotics in...

11/06/2014

| Publication | Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis

A group of researchers from the Weizmann Institute of Science (Israel) showed  that the gut microbiota of mice and humans, both in composition and functional profiles, follows diurnal oscillations. These are marked by the feeding rhythms of...

10/07/2014

|Publication| Rapid Core-Genome Alignment and Visualization for Thousands of Microbial Genomes

A group of researchers from the Center for Bioinformatics and Computational Biology in Maryland has recently presented a core-genome alignment and visualization tool, the Harvest suite. It responds to the need of quickly comparing the hundreds of...

10/02/2014

|Publication| Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo

A group of scientists from the University of London have studied through Comparative Genomics how Staphylococcus aureus, a commensal and major pathogen of humans and animals, acquires after colonization of different host species a number of...

09/22/2014

|Publication| Gut Microbiome helps to increase the efficacy of some vaccines

A group of scientists from the Emory Vaccine Center linked early expression of TLR5, which encodes a protein that enables immune cells to sense flagellin, the protein which forms the appendages of bacteria, and the strength of the antibody response after...

09/22/2014

|Publication| Cardiac complications following Pneumonia might be caused by Microlesions in the heart tissue formed by Streptococcus pneumoniae

Hospitalization of the elderly for pneumonia is often followed by cardiac complications. A group of scientists from the University of Texas Health Science Center at San Antonio (UTHSCSA) have found that Streptococcus pneumoniae, the bacteria that...

09/16/2014

|Publication| 99 Ebola virus whole-genome sequences help elucidate its epidemiology

Gire et al. have recently published a study in which they have sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone. They have noticed a large inter-and intrahost genetic variation, which made possible for them to stablish the Ebola epidemiology....

09/16/2014

|Publication| Commensal bacteria protect against food allergen sensitization

More than 20 years ago it was proposed that reduction in the exposure to infectious microbes was depriving our immune system of the immunoregulatory stimulation needed to protect us from allergies. More recently, groups of researchers have shown its support...

09/16/2014

|Publication| Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences.

A group of researchers from NYU Langone Medical Center have studied how low-dose penicillin (LDP), administered from birth, affects the expression of genes related to immunity and provokes metabolic alterations by disruption of the microbiota. Also, LDB...

09/16/2014

|Publication| Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients

Fecal Microbiota Transplantation (FMT), also known as a stool transplant, refers to the infusion of stool from a healthy individual into the GI tract of the patient to restore his entire fecal microbiota. This process has been gaining attention since...

09/16/2014

|Publication| Integrated whole-genome sequencing and temporospatial analysis of a continuing Group A Streptococcus epidemic

Data analysis remains the bottleneck in genome sequence-based investigations. A group of researchers improved an analysis pipeline that allowed them to accurately identify polymorphisms for 90 strains of GroupA Streptococcus in less than 24h after obtaining...