454 sequencing

454 sequencing technology is a next generation sequencing system for ultra-high-throughput DNA sequencing. It allows to obtain long, highly accurate sequence reads with an easy sample preparation. It is possible to generates 400 million high quality bases per 10 hour instrument run.


The system is appropriate for de novo sequencing, for resequencing of whole genomes and target DNA regions, for study of viral variants, for detection of points with genetic polymorphisms, for transcriptome analysis and for RNA analysis.


We offer bioinformatics services to obtain a more comprehensive view of your 454 data. Our multidisciplinary team can help you to extract more knowledge from your 454 data.


We also provide specific expert consultancy or establish research contracts. (See our research lines and our publications)


Studies using 454 sequencing are contributing to important advances in diverse research fields such as cancer and infectious diseases, drug discovery, marine biology, anthropology, evolution and ecology, plants and agricultural biotechnology, human genomics, ...