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assembly refinement

NGS data assemblies have most of the time many unresolved contigs, collapsed repeats, ... These issues can be solved through a mix of alternative assembly and base calling tools, annotation and in depth analysis of contig ends and specific repeat analysis.

 

Based on information like gene structure, gene architecture, local similarities and motifs analysis of the contigs ends, genome comparison, we are able to greatly improve and refine both de novo and reference assemblies; this leads to, for example, important simplification and error-rate reduction in subsequent analysis processes, such as annotation.

 

Contact us, or read the assembly refinement brochure for more information.